The coronavirus disease 2019 (COVID-19) pandemic caused by the emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global public health, and there is an urgent need to [...]
Strategies to enhance the induction of high magnitude T cell responses through vaccination are urgently needed. Major histocompatibility complex (MHC) class II–associated invariant chain (Ii) [...]
Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults
Originally published on Journal of Infection 2019 Feb 8. pii: S0163-4453(19)30038-6. doi: 10.1016/j.jinf.2019.02.003. Green CA, Sande CJ, Scarselli E, Capone S, Vitelli A, Nicosia A, Silva-Reyes [...]
Originally published on Expert Rev Vaccines. 2017 Dec 16(12):1241-1252. Vitelli A, Folgori A, Scarselli E, Colloca S, Capone S, Nicosia A.
Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections
Originally published on Sci Transl Med. 2015 Aug 12;7(300):300ra127. Taylor G, Thom M, Capone S, Pierantoni A, Guzman E, Herbert R, Scarselli E, Napolitano F, Giuliani A, Folgori A, Colloca S, [...]
Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge.
Originally published on Nat Med. 2014 Oct;20(10):1126-9. Stanley DA., Honko AN., Asiedu C., Trefry JC., Lau-Kilby AW., Johnson JC., Hensley L., Ammendola V., Abbate A., Grazioli F., Foulds KE., [...]
Massive parallel screening of phage libraries for the generation of repertoires of human immunomodulatory monoclonal antibodies
Originally published on MAbs. 2018 Oct;10(7):1060-1072. doi: 10.1080/19420862.2018.1496772. Epub 2018 Aug 1. Sasso E, D’Avino C, Passariello M, D’Alise AM, Siciliano D, Esposito ML, [...]
Originally published on N Engl J Med. 2016 Apr 28;374(17):1635-46. doi: 10.1056/NEJMoa1411627. Epub 2015 Jan 28. Ewer K, Rampling T, Venkatraman N, Bowyer G, Wright D, Lambe T, Imoukhuede EB, [...]
Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults
Originally published on Sci Transl Med. 2015 Aug 12;7(300):300ra126. Green CA, Scarselli E, Sande CJ, Thompson AJ, de Lara CM, Taylor KS, Haworth K, Del Sorbo M, Angus B, Siani L, Di Marco S, [...]